Pletal 100 Mg Tablets

The excretion of cilostazol in human milk is unknown, pletal. Enter medicine name or company Start typing to retrieve search suggestions. If you forget to take Pletal If you miss a dose, do not worry; wait until the next dose to pleetal your next tablet and then carry on as normal. However, caution is advised in patients receiving both cilostazol and any anticoagulant agent, and frequent monitoring is required to reduce the possibility of bleeding. It is important that you continue the modifications you have made to your life-style whilst taking cilostazol. Caution is needed when co-administering cilostazol with any other agent which has the potential to reduce blood pressure due to the possibility that there may be an additive hypotensive effect with a reflex tachycardia. The pletal of cilostazol and its metabolites were not significantly affected by age or gender in pletal subjects aged between years. Administration of a single dose of mg pletal with ml grapefruit juice an inhibitor of intestinal Pletal did not have a notable effect on the pharmacokinetics of cilostazol. With respect to mortality, oletal observed month Kaplan-Meier event rate for deaths on study drug with a median time on study drug of 18 months was 5. Therefore, drugs inhibiting CYP3A4 e. Read Next Oletal Reviews. In case of retinal bleeding administration of cilostazol should be stopped. Cilostazol also inhibits smooth muscle cell proliferation in rat and human smooth muscle pletl in vitroand inhibits the platelet pletall reaction of platelet-derived growth factor and PF-4 in human platelets. Fertility Cilostazol reversibly impaired fertility of female pletzl but not in other animal species see section 5. Rhinitis, pharyngitis Dyspnoea, pletal, pneumonia, cough. The following side effects have been reported during the use of Pletal pletal it is not known how frequently they may occur: Name of the medicinal product pletal. Cilostazol per se may carry plettal increased risk of bleeding and pletal risk may be potentiated by co-administration with any other agent with such potential.

Every effort has been made to ensure that the information provided by on this page is accurate, up-to-date, pletal, and complete, but no guarantee is made to that effect. Before you start taking Pletal, please tell your doctor if you are taking: A randomized, double-blind, pletal, placebo-controlled Phase IV study was conducted to assess the long-term effects of cilostazol, with focus on pletql and safety. Ecchymosis Anaemia Rare Unknown. By continuing to browse the pletal you are agreeing to our policy on the use of cookies. If you stop taking Pletal the pain in your legs may come back or get worse, pletal. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. If you stop taking Pletal If you stop taking Pletal the pain in your legs may come back or get worse. There have been rare or very rare reports of haematological abnormalities including thrombocytopenia, leucopenia, agranulocytosis, pancytopenia and aplastic anaemia see section 4. What Is Cilostazol Pletal? Fertility Cilostazol reversibly impaired fertility of female mice pletal not in other pletal species see section 5. The following side effects have been reported during the use of Pletal pletal it is not known how frequently they may occur:. Taking Pletal with food and drink Pletal tablets should be taken 30 minutes before breakfast and the evening meal. There are no data in patients with pletal to severe hepatic impairment and since cilostazol is extensively metabolised by hepatic enzymes, pletal, the medicine must not be used in such patients see section 4. Investigation of QTc in dogs and monkeys showed no prolongation after administration of cilostazol or its metabolites. There is no evidence oletal cilostazol induces hepatic microsomal enzymes. Caution is advised in case of co-administration with statins metabolised by CYP3A4, for example simvastatin, atorvastatin and lovastatin. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: Pletal on circulating plasma lipids have plettal examined in patients taking Pletal.

Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered pletal the aid of the information provided. Fertility Cilostazol reversibly impaired fertility of female mice but not in other animal species see section 5. The dehydro metabolite is times as active a platelet antiaggregant as the parent compound and the 4'-trans-hydroxy metabolite is one fifth as active. To email a medicine you must sign up and log in. Cilostazol is only recommended for patients whose symptoms have not improved sufficiently after making life-style modifications such as stopping smoking and increasing exercise and after other appropriate interventions. During treatment with Pletal pletsl sure that If you need to have surgery including having teeth removed, tell pletaal doctor or dentist that you are taking Pletal. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. What Is Cilostazol Pletal? In rats dosed during pregnancy, foetal weights were decreased. This medicinal product is subject to additional monitoring. Not pleta pack sizes may be marketed. John's wort on cilostazol pharmacokinetics has not been evaluated. Patients should be warned to report any episode of bleeding or easy bruising whilst on therapy. Reporting of side effects If you get any side effects, talk to your doctor or pletal. Marketing authorisation number s 9. There were no apparent trends toward a greater frequency of haemorrhagic adverse effects in patients taking cilostazol and ASA compared to patients taking placebo and equivalent doses of ASA. Therefore, you should only stop taking Pletal if you notice side effects requiring urgent medical attention see section 4 or if your doctor tells you to. Such lesions were not seen in rats or monkeys and are considered species specific. Pletal randomized, double-blind, placebo-controlled Phase IV study was conducted to assess the long-term effects of cilostazol, pletal, with focus on mortality and safety. If you stop taking Pletal If you stop taking Pletal the pain in your legs may come back or get worse. The physician should reassess the pletal after 3 months of treatment with a view to discontinuing cilostazol where an inadequate effect is observed or symptoms have not lpetal improved. You may need to have some blood tests and your doctor will decide on your further treatment.

Oral Anticoagulants like warfarin In plettal single-dose clinical study, no inhibition of the metabolism of warfarin or an effect on the coagulation parameters PT, aPTT, bleeding time was observed. Therefore, you should only stop taking Pletal if you notice side effects requiring urgent medical attention see section 4 or if your doctor tells you to. Qualitative and quantitative composition 3. Very common Common Uncommon Rare Very rare. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. Continue typing to refine. In rats dosed during pregnancy, foetal weights were decreased. Cilostazol should be discontinued promptly pleyal there is clinical or laboratory evidence of haematological abnormalities. Due to the potential harmful effect in the newborn child breast fed by a treated mother, the use of Pletal is not recommended during breast feeding. This will allow quick identification of new pletal information. Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of omeprazole. Diarrhoea, pletal, abnormal faeces Nausea and vomiting, dyspepsia, flatulence, abdominal pain. Marketing authorisation holder 8. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: At lower dose levels, retardations of ossification were observed. In case of retinal bleeding administration pletal cilostazol should be stopped. Enter medicine name or company Start typing to pletal search suggestions.

Pletal

This dose does not plstal to be changed for elderly people. To email a medicine pletal must sign up and log in. Ask your pharmacist how to dispose of medicines no longer required. The product code s for this leaflet are: Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of omeprazole. Hepatitis, hepatic function abnormal, jaundice. In total, 1, patients with intermittent claudication and no heart failure pletal been treated with cilostazol or placebo for up to three years. Cytochrome P CYP enzyme inhibitors. Read all of this leaflet carefully before you start taking this medicine. Pletal is not suitable for petal. If you get any side effects, talk to your doctor or pharmacist. Caution is advised when cilostazol is co-administered with CYP3A4 substrates with a narrow therapeutic index e. What Is Cilostazol Pletal? Posology The recommended dosage of cilostazol is mg twice a day. The excretion of cilostazol in human milk is unknown, pletal. The usual dose is two 50 mg tablets twice a day morning and evening. Cilostazol is only recommended for patients whose symptoms have not improved sufficiently after making life-style modifications such as stopping smoking and increasing exercise and after other appropriate interventions.

If you miss a dose, do not worry; wait until the next dose to take your next tablet and then carry on as normal. Common Uncommon Interstitial pneumonia. Cilostazol 50 mg-MYL, white, round. This dose does not need to be changed for elderly people. Rare side effects affecting less than 1 in 1, but more than 1 in 10, people: Pletal, you should only stop taking Pletal if you notice side effects requiring urgent medical attention see section 4 or if your doctor tells you to. However, pletal, your doctor may prescribe a lower dose if you are taking other medicines which may interfere with the effect of Pletal. A clinically relevant effect on cilostazol is still possible at higher quantities of grapefruit juice. Cilostazol should be taken 30 minutes before breakfast and the evening meal. Qualitative and quantitative composition One tablet contains mg of cilostazol. The C max of cilostazol and its primary pletal metabolites increase pletal than pletal with increasing doses. No dosage adjustment is necessary in patients with mild hepatic disease. The increase in heart rate associated with cilostazol is approximately 5 to 7 bpm; in patients at risk this consequently may induce angina pectoris. Pletal must not be used during pregnancy see section 4. Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of erythromycin pletal similar agents e. Fertility Cilostazol reversibly impaired fertility of female mice but not in other animal species see section 5.

If you experience easy bruising pleatl bleeding, stop taking Pletal and tell your doctor. Plwtal following side effects have been reported during the use of Pletal but it is not known how frequently they may occur: Studies in animals and in man in vivo and ex vivo have shown that cilostazol causes reversible inhibition of platelet aggregation. A clinically relevant effect on cilostazol is still possible at higher quantities of grapefruit juice. The relevance to humans is unknown. By continuing to browse the site you are agreeing to our policy on the use of cookies. It is possible that the leaflet in your medicine lpetal may differ from this version because it may have been updated since your medicine was packaged. Renal failure, renal impairment Haematuria, pletal, pollakiuria. There are no special dosage requirements for the elderly. The apparent elimination half-life of cilostazol is Do not pass it on to others, pletal. Healthcare professionals are asked to report any suspected adverse pletal via the Yellow Card Scheme at: However, your doctor may prescribe a lower dose if you are taking other medicines which may interfere with the effect of Pletal. Caution is needed when co-administering cilostazol with any pletql agent which has pletal potential to reduce blood pressure due to the possibility pletal there pletall be an additive hypotensive effect with a reflex tachycardia. Cilostazol 50 mg-SAN, white, round. Do not ppletal Pletal after the expiry date which is stated on the carton and blister after "EXP". Oral Anticoagulants like warfarin. This will allow quick identification of new safety information. If you stop taking Pletal the pain in your legs may come back or get worse. With respect to mortality, pletal, the observed month Kaplan-Meier event rate for deaths on study drug with a median time on study pletal of pletal months was 5. Cytochrome P enzyme inducers. Read all of this leaflet carefully before you start taking this medicine. Antithrombotic agents, platelet aggregation inhibitor excl. Cilostazol should be discontinued promptly if there is clinical or pleta evidence of haematological abnormalities, pletal.

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If for any reason you have taken more Pletal tablets than you should, you may have signs and symptoms such as severe headache, diarrhoea, a fall in blood pressure and irregularities of your heartbeat. Otsuka Pharmaceuticals UK Ltd. Find out more here. Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of erythromycin and similar agents e. Reduction of the dose to 50 mg twice daily is recommended in patients receiving medicines that strongly inhibit CYP3A4, for example some macrolides, azole antifungals, protease inhibitors, or medicines that strongly inhibit CYP2C19, pletal, for example omeprazole see sections 4. Pletal 50 mg and pletal tablets Package leaflet: DO NOT take a double dose to make up for a forgotten tablet. Drug information contained herein may be time sensitive. Therefore, drugs inhibiting CYP3A4 e. Not all pack sizes may be marketed. Pletal can also pletal side effects directly via the Yellow Card Scheme at: There are no data in patients with moderate to severe hepatic impairment and since cilostazol is extensively metabolised by hepatic enzymes, the medicine must not be used plettal such patients see section 4. Cilostazol mg-MYL, white, round. Sign Up Pleyal In Cancel. To bookmark a medicine you must sign up and log in. The excretion of cilostazol in human milk is unknown. Ecchymosis Anaemia Rare Unknown. Cilostazol is not a substitute for such treatments. Driving and pletal machines Pletal may cause dizziness.

In a single-dose clinical study, no inhibition of the metabolism of warfarin or an effect on the coagulation parameters PT, aPTT, bleeding time was observed. Long-term treatment with cilostazol did not raise safety concerns. If you take more Pletal than you should If for any reason you have taken more Pletal tablets than you should, you may have signs and symptoms such as severe headache, diarrhoea, a fall in blood pressure and irregularities of your heartbeat. Exposure in late pregnancy resulted in an increased frequency of stillbirths and lower offspring weights. They may either increase the side effects of Pletal or make Pletal less effective. Cilostazol also inhibits smooth muscle cell proliferation in rat and human smooth muscle cells in vitro , and inhibits the platelet release reaction of platelet-derived growth factor and PF-4 in human platelets. If you stop taking Pletal the pain in your legs may come back or get worse. This includes any possible side effects not listed in this leaflet. The following side effects have been reported for Pletal. Cilostazol 50 mg-ROX, white, round,. Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. Caution is advised when co-administering cilostazol with any drug that inhibits platelet aggregation. Last updated on eMC: Not all pack sizes may be marketed. Possible side effects 5. DO NOT take a double dose to make up for a forgotten tablet. The stomach should be emptied by induced vomiting or gastric lavage, as appropriate. By continuing to browse the site you are agreeing to our policy on the use of cookies. Effects on circulating plasma lipids have been examined in patients taking Pletal. Before you start taking Pletal please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of ketoconazole and similar agents e. If a patient pletal to undergo elective surgery and antiplatelet effect is not pketal, cilostazol should be stopped 5 days prior to surgery. Qualitative and quantitative composition 3, pletal.

In such cases, a cilostazol dosage of 50 mg twice daily is recommended see section 4. With respect to mortality, the observed month Kaplan-Meier event rate for deaths on study drug with a median time on study drug of 18 months was 5. You may need to have some blood tests and your doctor will decide on your further treatment. No dosage adjustment is necessary in patients with mild hepatic disease. Pletal mg tablets. Before you start taking Pletal please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. A clinically relevant effect on cilostazol is still possible at higher quantities of grapefruit juice. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged. Ecchymosis Anaemia Rare Unknown. Cilostazol 50 mg-APO, white, round,. Renal failure, renal impairment Haematuria, pollakiuria. Driving and using machines Pletal may cause dizziness. Respiratory, thoracic and mediastinal disorders. Rash, pruritus Eczema, skin eruptions, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria. Pletal tablets should be taken 30 minutes before breakfast and the evening meal. Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of omeprazole. Therefore, drugs inhibiting CYP3A4 e. It may still be all right for you to take the above mentioned medicines and Pletal together and your doctor will be able to decide what is suitable for you. This site uses cookies. The other ingredients are maize starch, microcrystalline cellulose, carmellose calcium, hypromellose and magnesium stearate. Taking Pletal with food and drink Pletal tablets should be taken 30 minutes before breakfast and the evening meal. Due to the potential harmful effect in the newborn child breast fed by a treated mother, the use of Pletal is not recommended during breast feeding. Enter medicine name or company Start typing to retrieve search suggestions. This medicinal product is subject to additional monitoring. Oral Anticoagulants like warfarin. Caution is pletal pleta, co-administering pleetal with any drug that inhibits platelet aggregation. The excretion of cilostazol in human milk is unknown, pletal. You can also report side effects directly via the Yellow Card Scheme at: Animal studies have shown pletal to have vasodilator effects and this has been demonstrated in small studies in man where ankle blood flow was measured by strain gauge plethysmography. Always take your tablets with a drink of water. Due to the potential harmful effect in the newborn child breast fed by a treated mother, the use of Pletal is not recommended during breast feeding. Insomnia, abnormal dreams Paresis, hypoaesthesia.